It is well known that peptides form the backbone of enormously complex proteins. How do these peptides fragment, when irradiated with UV light? Research in our group, in collaboration with the Reilly group, focuses on the investigation of UV induced fragmentation of peptides, thereby facilitating the identification and quantification of chemical modifications of peptides, as well as unraveling new types of structures and patterns. In the supramolecular front, our group examines the practical utility of the CH hydrogen bond, hitherto assumed to be too weak to be of any practical significance at all. Electronic structure calculations from our group and experimental results from the Flood group are proving to be invaluable in unearthing the latent potential of the generally assumed “weak” C–H hydrogen bond.
Bio-organic and Supramolecular Chemistry
